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At 72 weeks, tirzepatide vs semaglutide produced 20.2% mean weight loss versus 13.7% in SURMOUNT-5, the first randomized head-to-head trial between them (NEJM, May 2025)

Semaglutide Associated with: Ozempic Wegovy Benefits include: Appetite suppression Reduced cravings Improved blood sugar control Consistent long-term weight loss Tirzepatide Associated with: Mounjaro Zepbound Benefits include: Dual GLP-1 and GIP hormone action Stronger metabolic response Often greater weight-loss outcomes than semaglutide ReflexMDs specific inventory depends on pharmacy access and regulatory availability

Similar content being viewed by others Introduction From 2000 to 2019, the Global Burden of Disease study showed a 0.48% annual increase in age-standardized disability-adjusted life years (DALYs) related to obesity, defined as a body mass index (BMI) 25 kg/m 2 1

Unmatched prices with no hidden fees Free + discreet shipping Confidential telehealth consultations Compounded GLP-1 can help you lose a significant amount of weightreal results, life-changing impact